Cipro, based on ciprofloxacin active substance, is a drug broad spectrum of applications, aimed at eliminating different infectious agents and producing a
strong bactericidal effect.
Ciprofloxacin is a representative of a second-generation of fluoroquinol. Cipro can be taken safely only after determining the type of pathogenic
The pharmacological properties of the antibacterial medication provide a broad spectrum of action, similar to the action of the fluoroquinolones, though
the drug demonstrates higher effectiveness.
Cipro is well absorbed within two hours after application; it enters the blood plasma after intravenous administration after half an hour. The process of
withdrawal of the drug takes approximately 4 hours.
The active substance builds in the organs and tissues; it is characterized by an increased blood-brain barrier speed. 40% of the medication is excreted in
the urine within the 1st day after the application in an unmodified state, a small portion is excreted in the bile.
Indications for use
Cipro indications are not much different from the ones of fluoroquinolones group preparations. The drug is assigned in a broad variety of respiratory
tract, bone and joint, soft tissue, skin and gastrointestinal tract infections.
The preparation’s efficiency has been confirmed in treatment of salmonella, shigella; meningitis, post-operative and gonococcal infections, sepsis and
other suppurative and inflammatory processes. In case of genitourinary system infections the drug has a good effect due to the rapid penetration of the
kidneys and the long-term isolation. The medication is also prescribed to treat infections in patients with cancer. The treatment typically lasts up to 15
At serious flow of infectious disease and the inability to take medicine in pill form, the option of intravenous administration may be considered. During
the course, drinking plenty of fluids is required. The pills are recommended be taken on empty stomach to speed up the absorption of the substance. Cipro
can be taken regardless of meals.
To avoid overdose should take the drug under the control of the patient. In the event of an overdose, it is necessary to carry out gastric lavage and
adjust abundant flow of fluid in the human body.
The list of contraindications is narrowed to epilepsy, hypersensitivity, pregnant women and young adults under 18 years old. When kidney disease the drug
is used under special control by tracking the rate of blood clearance of creatinine. Cipro is not recommended to be taken simultaneously with antacid
remedies, as they decrease the acidityof the stomach, which can significantly reduce the effectiveness of treatment.
Dosage and administration
Mentioned below are the average doses appointed depending on the nature of the problem:
Uncomplicated infections 0,125 2g daily admission
Complicated infections (including urinary and respiratory tract ones) 500 mg twice daily during 10 days
Very severe cases of infectious diseases 0.75 g twice a day
Acute gonorrhea or cystitis 0.1 grams per day
Inflammation of the prostate gland in a cavity 500 mg twice a day during 14 days
Enteritis caused by bacterial flora 500 mg in the morning and evening
Gram-negative pathogenic microflora 500 mg in the morning and evening
According to the insert, the preparation is not likely to cause significant side effects; although, nausea, dizziness, anxiety, and a range of other
symptoms may manifest.